a CD-ROM called The Herbalist by David L. Hoffman, BSc
herb is prepared from the ripe fruits of Chinese magnolia vine,
Schizandra chinensis, and is extensively used in Oriental medicine.
Since the initial isolation of lignans (schizandrin and deoxyschizandrin)
from its seed oil, more than 30 lignans have been isolated and
given to 189 patients manifesting chronic viral hepatitis with elevated
serum GPT levels. 107 were given 100 mg. of the extract (= 1.5 g of the
herb) 82 cases received a liver extract-vitamin E complex as control.
After 16-24 weeks of treatment, 73 of those treated with Schizandra
showed a fall of serum GPT to normal levels. No rebound was observed
after withdrawal of the herb. The rate of effectiveness in lowering the
GPT level was 68.2% in the treated group and 44% in the control group.
The average time needed for lowering the level to normal was about 4
weeks for the treated group and 8 weeks for the control group.
Schizandra was effective in relieving symptoms of sleeplessness,
fatigue, abdominal tension, and loose bowels. No side-effects were