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Caution: That Dose May Be Too High
By ABIGAIL
ZUGER (NYT) 1657 words
Late Edition
- Final , Section F , Page 1 , Column 1
http://query.nytimes.com/gst/abstract.html?res=F40B14FC3C540C748DDDA00894DA404482
ABSTRACT
- Georgetown University study finds that 21 percent of 354
prescription drugs released from 1980 to 1999 had their
recommended doses corrected at later date, almost always to
lower dose; finds that drugs released in last five years are
even more likely to have instructions changed than older ones;
findings support longstanding concerns among some experts that
drugs are being studied at excessively high doses to emphasize
their effects and marketed at same high doses to maximize
profits; . .
.Twenty percent of prescription drugs are marketed with
instructions for use that must later be corrected by the
manufacturer, researchers say -- almost always to lower the
recommended dose or to warn that the drug may be hazardous to
certain patients.
Drugs released in the last five years are even more likely
to have their instructions changed than older ones.
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