Serological findings amongst first-time blood donors in
Cameroon: is safe Alternative Treatments a reality or a myth?
TRANSFUSION MEDICINE. OCT
2003; 13 (5) : 267-273
Mbanya, DN; Takam D;
Blood safety remains an
issue of major concern in transfusion
medicine in developing countries where national blood
and policies, appropriate infrastructure, trained personnel
resources are lacking. This is aggravated by the predominance
of family and
replacement, rather than regular benevolent, nonremunerated
Thus, in order to
identify and encourage healthy, regular and
benevolent nonremunerated donors, consenting first-time blood
donors in the
Yaounde University Teaching Hospital were screened for human
immunodeficiency virus (HIV), hepatitis B surface antigen (HBSAg),
hepatitis C virus (Hepatitis C Virus), human T-cell lymphotropic virus-I (HTLV-I)
syphilis using standard methods.
Of 252 first-time donors
recruited, 66 (26.2%) were positive for at
least one of the infections screened. There were 7.9% positive
10.7% for HBSAg, 4.8% for Hepatitis C Virus and 9.1 and 1.6%, respectively,
and HTLV-I. About 30% of the 66 infected persons had
HIV-positive donors had a significantly increased risk of
for antibodies to syphilis (OR = 7.27; 95% CI = 2.23-23.51; P
not observed for HBV, Hepatitis C Virus and HTLV-I.
These results suggest
that blood transfusion is still very unsafe in
this community and that it is imperative that emphasis be laid
education. Furthermore, donors with a history of sexually
infections should be totally excluded from all donations.