Guggul herb:
Guggul (Commiphora mukul) is a highly valued botanical medicine used in
Ayurveda.
It is used for rheumatoid arthritis, and lipid disorders. The classic
Ayurveda medical text, described in detail the usefulness of this herb
for treatment of obesity and other disorders of fat, including "coating
and obstruction of channels". Encouraged by the Ayurvedic description of
this herb for lowering cholesterol, scientists have conducted clinical
trials to test the effectiveness of this herb in disorders of lipid
metabolism and for lowering weight. The research resulted in the
development of a natural cholesterol lowering substance that is safer
and more effective than many cholesterol-lowering drugs.
Origin
The mukul myrrh (Commiphora mukul) tree is a small, thorny plant
distributed throughout India. Guggul and gum guggulu are the names given
to a yellowish resin produced by the stem of the plant.
Chemical
composition / key active constituents
Ketone fraction that
is extracted from the resin contains the most potent cholesterol
lowering components. This is composed of C21 or C27 steroids, with the
major components being Z- and E-guggulsterone.Guggul contains resin,
volatile oils, and gum. The extract isolates ketonic steroid compounds
known as guggulsterones. These compounds have been shown to provide the
lipid-lowering actions noted for guggul.
Pharmacology
Guggul significantly
lowers serum triglycerides and cholesterol as well as LDL and VLDL
cholesterols (the "bad" cholesterols). At the same time, it raises
levels of HDL cholesterol (the "good" cholesterol), inhibits platelet
aggregation, and may increase thermogenesis through stimulation of the
thyroid, potentially resulting in weight loss. In Ayurvedic medicine, it
is used to remove "Ama", or deposits of waste or toxic material in the
body, including mucus and mineral deposits in the joints, thus reducing
a
possible cause of sluggishness, inflamed joints, and many other
conditions. A direct anti-inflammatory effect has been observed for
guggulsterones. Guggul has also been shown to reduce the stickiness of
platelets-another effect that lowers the risk of coronary artery
disease.
Remedies For
High cholesterol
levels, High triglyceride levels, Atherosclerosis, Obesity.Guglipid
offers considerable benefit in preventing and treating atherosclerotic
vascular disease (Heart disease).It is most effective in lowering LDL
cholesterol and triglycerides. It also raises the level of good
cholesterol (HDL). It is used as expectorant i.e. in cough problems.
This guggul has great effect in preventing heart atherosclerosis, or
narrowing of the arteries.
Dosage
Daily
recommendations for guggul are typically based on the amount of
guggulsterones in the extract. A common intake of guggulsterones is 25
mg three times per day. Most extracts contain 5-10% guggulsterones.
For a 5 percent guggulsterone extract, this translates to an effective
dose of 500 milligrams three times per day.
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